Neuromuscular blockers are the commonest cause of anaphylaxis in perioperative settings. The pathological process involves IgE-mediated hypersensitivity reaction with release of vasoactive inflammatory substances in response to exposure to the causative agent. Here, we present a case of atracurium-induced anaphylaxis in a patient scheduled for open cholecystectomy. The patient was treated with epinephrine. The surgery was done after a gap of 1 month post recovery. This time induction was done with vecuronium and the surgery was completed uneventfully.

Keywords: anaphylaxis; atracurium; epinephrine; general anaesthesia; IgE hypersensitivity; muscle relaxant.

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Dr Ritu Rani

Dermatologist, Civil Hospital Kangra, H.P., India