Title: An Observational Study on Serum Ferritin Level in Dengue Fever and Its Correlation with Severity of Dengue Fever
Authors: K. Gokul Bharathi, R Aswinth, S. Sudarshan
DOI: https://dx.doi.org/10.18535/jmscr/v7i10.105
Abstract
Aims and Objectives: To study the serum ferritin level in dengue fever and its correlation with severity of dengue fever
Methods: The study was performed on patients admitted for dengue fever in Rajah Muthiah Medical College and Hospital under the Division of General Medicine from October 2017 to September 2019.After satisfying the inclusion and exclusion criteria 50 dengue IgM positive patients were included in this study. Their serum ferritin levels on the day of admission was measured. The relationship between serum ferritin levels and platelets and severity of dengue fever was observed
Results : There was significant correlation between serum ferritin levels and thrombocytopenia (p=0.006).Patients with increased ferritin levels had significant decrease in platelet count. Bleeding tendencies were found to be higher in patients who had increased ferritin levels and thrombocytopenia.
Conclusion: Serum ferritin levels were increased in dengue fever. Patients with high ferritin levels were found to have increased incidence of thrombocytopenia. Hence high ferritin levels can be used as a indicator for assessing disease severity and prognosis of dengue fever patients. Those patients with high serum ferritin levels should be monitored carefully.