Lofgren's syndrome is an acute form of sarcoidosis, characterized by the triad of polyarthritis, hilar adenopathy and erythema nodosum. Here, we report a case who presented with polyarthralgia and rash. Skin biopsy from rash revealed erythema nodosum. Chest imaging showed enlarged multiple mediastinal lymph nodes.

1. Mana J, Gomez-Vaquero C, Salazar A, Valverde J, Juanola X, Pujol R. Periarticular ankle sarcoidosis: a variant of Lofgren's syndrome. J Rheumatol. 1997; 24(1):239.

2. Bogunia-Kubik K, Tomeczko J, Suchnicki K, Lange A. HLA-DRB1 03, DRB1 ll or DRB1 12 and their respective DRB3 specificities in clinical variants of sarcoidosis. Tissue Antigens 57: 87-90, 2001.
3. Criado E, Sanchez M, Ramıŕ ez J, Arguis P, de Caralt TM, Perea RJ, Xaubet A. Pulmonary sarcoidosis: typical and atypical manifestations at high-resolution CT with pathologic correlation. Radiographics. 2010 Oct; 30(6):1567-Med Case Rep: Volume 3 (2017)
4. Ohta H, Tazawa R, Nakamura A, et al. Acute-onset sarcoidosis with erythema nodosum and polyarthralgia (Lofgren's syndrome) in Japan: a case report and a review of the literature. Intern Med. 2006; 45(9):659-662.

Dr Srikant Sharma

Senior Consultant Department of Internal Medicine, Moolchand Medcity, New Delhi