Abstract

Objective: In recent years lots of interest has been shown in the area of detecting in Vitamin D deficiency in patients suspected of Osteoporosis and Osteomalacia. While the techniques of assay have improved the need and significance of such studies. Raising the treatment cost for patients may not be justified in many cases. The aim of present study was to determine the evaluation of Vitamin D level in the different age group of woman attending in tertiary care hospital and also validity of its results.

Materials and Methods: A total of 96 woman with age group ranges from 21 to 70 years attending in the different OPD and IPD  with different bony or non bony complains were included in the study. After thorough clinical history, all the patients were subjected to proper clinical examination and referred to our department for Vitamin D estimation. Quantitative determination of Vitamin D estimation was done by fully automated Architect machine supplied by Roche pharma by CMIA (Chemiluminiscent Microparticle Immunoassay) methods.

Result: Out of the 96 woman 38 (39.58%) women were belonged to rural areas where as 58 (60.42%) woman from the urban side. Test value showed that Vitamin D level was sufficient in age between 21 to 30 years. Between 31- 40 years of age 25 % woman were found to be deficient level of vitamin D and 33.33 % woman has insufficient level of vitamin D. Age between 41-50 years 60 % woman had deficient level of vitamin D and 20 % were found to be Insufficient level of vitamin D. Age between 51-60 years 76.92 % woman had deficient level of vitamin D and 15.38 % were found to be Insufficient level of vitamin D. Age above 60 years 87.5 % were Deficient level of vitamin D and 3.125 % had Sufficient level of vitamin D. Rural background women with increase parity were found to be highly deficient level of vitamin D.

Conclusion: Measurement of Vitamin D status provides opportunities for Preventive and Therapeutic intervention. Serum Vitamin D level Estimation may be of value to select the patient who are suffering from Vitamin D deficiency and starting on empirical therapy of Vitamin D.