Title: A Study of Clinical Profile of Acute Pancreatitis and its Correlation with Biochemical and Radiological Parameters

Authors: Dr Manish Singh, Dr Achal Gupta, Dr Ashish Kumar Gupta, Dr Amit Jain

 DOI: https://dx.doi.org/10.18535/jmscr/v7i2.150

Abstract

Background: Acute pancreatitis runs a benign course, it is an inflammatory process of pancreas with varying involvement of regional tissues or remote organ systems.

Aims and Objectives

  1. To assess the clinical, biochemical and radiological profile of acute pancreatitis patients in our setup.
  2. To assess the response to treatment given with the respect to clinical, biochemical and radiological parameters.

Material & Methods: A prospective study was designed for sample of 67 patients admitted in department of surgery JAH group of Hospital G. R. medical college, Gwalior from period of FEB 2017 to JAN 2018. Based on clinical features, Lab values (serum amylase and serum lipase>3 from base line) and radiological finding, suggestive of acute pancreatitis were included and there course during hospital stay, treatment outcome was seen.

Results: Most patients of acute pancreatitis where of mild nature and patients recovered with no complications. Most Patients of moderate and severe pancreatitis recovered with complications. CECT Abdomen helped in early detection of patients with complications (55.25%) had normal findings. Majority of patients were cured (94%).

Conclusion: Acute pancreatitis was most common among patients who were in the 4th to 5th decade of life. Males predominated compared to females as all were alcoholic. Upper abdominal pain, nausea, vomiting and anorexia were the most common presenting symptoms of AP. Only cases of moderate and severe pancreatitis had complications rest improved, gallstone and alcohol were the most common etiological factors. Overall mortality in present study was 1.5% which significantly lower as compared to previous studies.

Keywords: Acute pancreatitis, Contrast Enhance Computed Tomography.

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