Abstract
Objective: The study was undertaken to re-evaluate the impact of isolated oligohydramnios on pregnancy and perinatal outcome.
Study Design: The study was a case-control study of 100 antenatal subjects in the Department of Obstetrics and Gynaecology in collaboration with Departments of Pathology and Radio-diagnosis, Jawaharlal Nehru Medical College, AMU, Aligarh, India over a period of two years (2012-2015). Two groups, study and control, based on their latest amniotic fluid assessment, were evaluated to determine the relationship between amniotic fluid index (AFI) and gestational age at delivery, induction of labour, meconium-stained liquor, cesarean delivery, birth weight, congenital anomalies, Apgar Score at 5 minutes and neonatal complications. Statistical evaluation was done using z-test. Subjects and controls were matched for age, social status and gravidity.
Results: AFI determinations in 100 pregnant females beyond 34 weeks gestation were used to allocate the patients to the study (AFI < 5cm, oligohydramnios) and the control (AFI 5-25cm) groups.
The mean gestational age at delivery was significantly lower in the study group. Labour was induced in a significantly higher number of patients in the study group compared to the control group. The incidence of cesarean delivery and congenital anomalies was significantly higher in the study group. There was no statistically significant difference in meconium-staining of liquor, birth weights, low 5-minute Apgar Score and neonatal complications between the two groups.
Conclusion: Oligohydramnios has been classically considered an indicator of fetal compromise and compromised utero-placental circulation but recent studies have called this into question. The present study suggests that the benefits of AFI in ante-partum surveillance need to be re-determined in a large, multi-center, randomised study.
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Corresponding Author
Sabahat Rasool
Fertility Consultant & Reproductive Medicine Specialist, Gynaecworld, Mumbai, India
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mob: 08879337870
DOI: https://dx.doi.org/10.18535/jmscr/v6i5.175
