Abstract
Aims and Objectives: To estimate and compare psychiatric co-morbidities in patients of Tuberculosis depending on duration, category of treatment and various other socio-demographic parameters.
Methodology: 240 patients of tuberculosis, between 18 to 60 years of age were taken into periodic study between April 2015 and March 2016, for evaluation of associated psychiatric co-morbidities at 10-15days and 55-60days after the registration under RNTCP DOTS. We collected information regarding psychiatric symptoms using M.I.N.I. (Mini International Neuropsychiatric interview).
Result: Male to female ratio was 1.3:1, the mean age group was 32.93 years, and majority (70%) of the patients belonged to lower socioeconomic group. Psychiatric co-morbidities evaluation in patient of tuberculosis on the study group at 10-15 days, patient taking category I treatment 59(24.58%). Among these 10(16.94%) had Major depressive episode, 8(13.55%) had Generalized anxiety disorder, 4(6.77%) had Obsessive-compulsive disorder, 2(3.38%) had Manic episode,4(6.77%) had Social phobia, 4(6.77%) had Alcohol dependence, 1(1.69%) had suicidal tendency, 4(6.77%) had Panic episode and 22(37.2%) had no psychiatric co-morbidities. As compared to category I, other categories were significantly and independently at high risk of psychiatric co-morbidities. Category II group had 75.47% and category IV group had 84% of psychiatric co-morbidities.
Conclusion: Depressive disorder is the most common psychiatric co-morbidity in patients of tuberculosis and more severe in category IV patient, at 10-15days after registration and majority of the patient belong to lower socioeconomic group.
References
- Herchline TE; Tuberclosis. Available from http:// emedicine. medscape.com/article/ 230802 overview. Last accessed on 5th May 2015 at 5 pm.
- Central TB Division, Government of India. TB India 2012. Revised National TB Control Programme. Annual Status Report. New Delhi: Central TB Division, Directorate General of Health Services, Ministry of Health and Family Welfare; 2012. Available from: http://tbc india.nic.in /pdfs/TB%20India%202012%20Annual%20Report.pdf. Last accessed on 10th May 2015 at 5 pm.
- West away MS, Wolmarans L; Depression and self-esteem: rapid screening for depression in black, low literacy, hospitalized TB patients. Social Science and Medicine, 1992; 35: 1311-15.
- Aghanwa HS, Erhabor GE; Demographic/ socioeconomic factors in mental disorders associated with TB in southwest Nigeria. Journal of Psychosomatic Research, 1998; 45: 35360.
- Rivinder NB; Depression. Available from http://www.webmd.com/depression/default.htm. Last accessed on 12th May 2015 at 6 pm.
- Vega, A. Sweetland, J. Acha et al., “Psychiatric issues in the management of patients with multidrug-resistant tuberculosis,” International Journal of Tuberculosis and Lung Disease, vol. 8, no.6,pp.749–759,2004.
- D. Natani, N. K. Jain, and T. N. Sharma, “Depression in tuberculosis patients: correlation with duration of disease and response to anti-tuberculous chemotherapy,” Indian Journal of Tuberculosis, vol.32, no.4, pp.195–198,1985.
- L.Panchal, “Correlation with duration and depression in TB patients in rural Jaipur district,” International Journal of Pharma and Bio-Sciences, vol.2,no.2,p. B.263,2011.
- Lecrubier Y, Sheehan D, Weiller E, Amorim P, Bonora I, Sheehan K, Janavs J, Dunbar G. The Mini International Neuropsychiatric Interview (M.I.N.I.), a short diagnostic interview: Reliability and validity according to the CIDI. European Psychiatry, 1997 ; 12 : 224-231.
- Sheehan DV, Lecrubier Y, Harnett Sheehan K, Janavs J, Weiller E, Bonora LI, Keskiner A, Schinka J, Knapp E, Sheehan MF, Dunbar GC. Reliability and validity of the Mini International Neuropsychiatric Interview (M.I.N.I.) according to the SCID-P. European Psychiatry, 1997 ; 12 : 232-241.
- Bansal, S.Chaudhri, and S.Agnihotri, “Impact of psychiatric morbidity and personality trait on treatment completion and default in patients taking directly observed treatment for tuberculosis,” European Respiratory Society, 2010.
- Williams and H. Kaur, “The psychosocial problems of pulmonary tuberculosis patients undergoing DOTS therapy (direct observed treatment short course therapy) in selected areas of jalandhar district, punjab,” Journal of Pharmacy and Biological Sciences, vol.1,no.1,pp.44–49,2012.
- Purohit, D.R., Purohit, S.D. and Dhariwal, M.L. 1978. Incidence of depression in Hospitalized T.B. Patients. Ind. J. Tub. 25(3): 147-150.
- Mathai, J.P., Ravindran, P., Joshi, P. and Sundaram, P. 1981. Psychiatric morbidity in pulmonary Tuberculosis: A clinical study. Ind. J. Psychiat. 23(1): 66-68.
- Bhatia, M.S., Dubey, K.K., Bhasin, S.K. and Sindhi, N. 2000. Psychiatric morbidity in Tuberculosis patients. Ind. Med. Gezette. 134(1): 5-6.
- Ige, O.M. and Lasebikan, V.O. 2011. Prevalence of depression in tuberculosis patients in comparison with non-tuberculosis family contacts visiting the DOTS clinic in a Nigerian tertiary care hospital and its correlation with disease pattern. Ment. Health Fam. Med. 8(4): 235-241.
- Yadav, B.S., Jain, S.C., Sharma, G., Mehrotra, M.L. and Kumar, A. 1980. Psychiatric morbidity in pulmonary tuberculosis. Ind. J. Tub. 27(4): 147-151.
- Deribew A, Deribe K, Reda AA, Tesfaye M, Hailmichael Y, Maja T, et al. Change in quality of life: a follow up study among patients with HIV infection with and without TB in Ethiopia. BMC public health 2013; 13: 408.
Corresponding Author
Dr Mukesh Tiwari
S.N.M.C. Agra (U.P.), India