Title: Correlation between APRI Index, MELD Sore and Child Pugh Score in Cirrhosis of Liver
Authors: Dr Jithin George, Dr Yeshavanth. G
DOI: https://dx.doi.org/10.18535/jmscr/v6i5.89
Abstract
Background: Liver cirrhosis is one of the most common cause of mortality. Among the causes alcoholism leads the first. Several scoring are available for the severity in cirrhosis and hepatic fibrosis.
Aims and Objectives: 1) To calculate APRI INDEX, child pugh score and MELD score in liver cirrhosis patients. 2) To find the correlation between APRI index, MELD score and Child pugh Score.
Materials and Methods: retrospective study among 50 patients with cirrhosis of liver. Cirrhosis of liver was confirmed by ultrasound and biochemical reports. Cirrhosis due to alcohol, Hepatitis B, Hepatitis C, NAFLD leading to cirrhosis were included in the study. APRI Index, Child Pugh Score, MELD Score were calculated and the correlation was obtained.
Results and Conclusion: The study found out the relationship of MELD Score and Child Pugh Score, and MELD Score and APRI index with significant p value. The study also showed significant p value between APRI Index and Child Pugh Score. The study also showed that raised APRI Index, higher Child Pugh classification and higher MELD score for patients who died in the hospital during the course of treatment. Among those who are dead, APRI index has a median value of 12.58 and Child Pugh score of median 15.Among the dead, had a MELD score of mean of 36.08 with standard deviation of 5.946.
Keywords: correlation, APRI Index, Child Pugh Score, MELD score.