Title: Comparative study of Olmesartan and Ramipril on reduction of raised diastolic blood pressure in patient with age more than 50 years
Author: Dr Amit Kumar Jha
DOI: https://dx.doi.org/10.18535/jmscr/v6i3.23
Abstract
Abstract
Hypertension is one of the risk factor for cardiovascular mortality. Antihypertensive drug is used to reduce blood pressure. In addition, angiotensin receptor blocker has shown beneficial effect for controlling target organ damage. Furthermore unlike ACE inhibitor these agents have side effect profile that is similar to that of placebo. Study was carried out for production of hypertension by psychogenic stress method. In pr esent work done by me antihypertensive effect of olmesartan and ramipril was compared with control and w ith each other .student ttest was done to compare result. It was found that blood pressure varied significantly across the three groups (P=.000).com pared to control group, blood cantly less in both olmesartan and ramipril (p=.000). Reduction of blood pressure with olmesartan was more than with ramipril at the end of work. Olmesartan is more efficacious than ramipril as far as blood pressure reduction is concerned.
Keyword: - olmesartan, ramipril, Antihypertensive effect.
