Title: Seasonality and First Ever Ischemic Stroke, In Sohag University Hospital, Sohag, Egypt
Authors: Hassan M. Elnady, Alaa Eldin Sedky, Al-Amir Bassiony Mohamed, Mahmoud A Hegab, Rasha Abd Elhameed Ali, Mohamed N. Thabit
DOI: http://dx.doi.org/10.18535/jmscr/v3i12.37
Abstract
Introduction: The effect of Seasonality on stroke has been reported in several regions worldwide. Nevertheless, there is inadequate data related to these phenomena in other areas. The aim of the present study was to investigate the possible effect of seasonality on first ever ischemic stroke (FEIS).
Patients and Methods:A total of 350 patients with first ever ischemic stroke (FEIS) admitted, within 24 hours of onset. Admission rates, risk factors, stroke severity, in hospital mortality and clinical and laboratory parameters on admission were compared in relation to different seasons.
Results: The admission rate for FEIS was highest in summer. Patients were more likely to be hypertensive during winter. The highest rate of cardiac diseases was found during winter. The most severe stroke was recorded during winter. Significantly, the highest value of leukocytic count and mean platelet volume and the lowest value of activated partial thromboplastin time were recorded during winter. The highest rates of in-hospital mortality were reported during winter.
Conclusion: Seasonality has a paramount effect on first ever ischemic stroke. Different risk factors have different influences on ischemic stroke in relation to seasonality.
Keywords: - acute cerebral infarction - ischemic stroke - risk factors - seasonal variation in ischemic stroke
References
1. McArthur K, Dawson J, Walters M. What is it with the weather and stroke? Expert review of neurotherapeutics. 2010;10(2):243-9. Epub 2010/02/09.
2. Diaz A, Gerschcovich ER, Diaz AA, Antia F, Gonorazky S. Seasonal variation and trends in stroke hospitalizations and mortality in a South American community hospital. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2013;22(7):e66-9. Epub 2012/05/23.
3. Palm F, Dos Santos M, Urbanek C, Greulich M, Zimmer K, Safer A, et al. Stroke seasonality associations with subtype, etiology and laboratory results in the Ludwigshafen Stroke Study (LuSSt). European journal of epidemiology. 2013;28(5):373-81. Epub 2013/02/07.
4. Ahmed A. Using Generic and Pesticide DRASTIC GIS-based models for vulnerability assessment of the Quaternary aquifer at Sohag, Egypt. Hydrogeol J. 2009;17(5):1203-17.
5. Programme S. SOHAG GOVERNORATE ENVIRONMENTAL PROFILE, . Ministry of State for Environmental Affairs. 2007.
6. Hatano S. Experience from a multicentre stroke register: a preliminary report. Bulletin of the World Health Organization. 1976;54(5):541-53. Epub 1976/01/01.
7. Dawson J, Weir C, Wright F, Bryden C, Aslanyan S, Lees K, et al. Associations between meteorological variables and acute stroke hospital admissions in the west of Scotland. Acta neurologica Scandinavica. 2008;117(2):85-9. Epub 2008/01/11.
8. Giua A, Abbas MA, Murgia N, Corea F. Climate and stroke: a controversial association. International journal of biometeorology. 2010;54(1):1-3. Epub 2009/08/27.
9. Chen R, Wang C, Meng X, Chen H, Thach TQ, Wong CM, et al. Both low and high temperature may increase the risk of stroke mortality. Neurology. 2013;81(12):1064-70. Epub 2013/08/16.
10. Wang Y, Levi CR, Attia JR, D'Este CA, Spratt N, Fisher J. Seasonal variation in stroke in the Hunter Region, Australia: a 5-year hospital-based study, 1995-2000. Stroke; a journal of cerebral circulation. 2003;34(5):1144-50. Epub 2003/04/05.
11. Diaz-Tapia V, Billeke P, Bustos C, Lopez M, Segovia D. [Seasonal variations in the symptoms of cerebrovascular disease. A study of hospital admission rates]. Revista de neurologia. 2004;39(12):1196-7. Epub 2004/12/31. Variaciones estacionales en la presentacion de la enfermedad cerebrovascular. Estudio de tasas de hospitalizacion.
12. Chang CL, Shipley M, Marmot M, Poulter N. Lower ambient temperature was associated with an increased risk of hospitalization for stroke and acute myocardial infarction in young women. Journal of clinical epidemiology. 2004;57(7):749-57. Epub 2004/09/11.
13. O'Connor A, Benelam B. An update on UK Vitamin D intakes and status, and issues for food fortification and supplementation. Nutrition Bulletin. 2011;36(3):390-6.
14. Deshmukh A, Pant S, Kumar G, Murugiah K, Mehta J. Seasonal variation in hypertensive emergency hospitalization. J Clin Hypertens (Greenwich). 2012;14(4):269-70. Epub 2012/03/31.
15. Fletcher RD, Amdur RL, Kolodner R, McManus C, Jones R, Faselis C, et al. Blood pressure control among US veterans: a large multiyear analysis of blood pressure data from the Veterans Administration health data repository. Circulation. 2012;125(20):2462-8. Epub 2012/04/21.
16. Kim YM, Kim S, Cheong HK, Ahn B, Choi K. Effects of heat wave on body temperature and blood pressure in the poor and elderly. Environmental health and toxicology. 2012;27:e2012013. Epub 2012/08/14.
17. Brook RD, Shin HH, Bard RL, Burnett RT, Vette A, Croghan C, et al. Can personal exposures to higher nighttime and early-morning temperatures increase blood pressure? J Clin Hypertens (Greenwich). 2011;13(12):881-8. Epub 2011/12/07.
18. Fustinoni O, Saposnik G, Esnaola y Rojas MM, Lakkis SG, Sposato LA. Higher frequency of atrial fibrillation linked to colder seasons and air temperature on the day of ischemic stroke onset. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2013;22(4):476-81. Epub 2013/04/09.
19. Sheth T, Nair C, Muller J, Yusuf S. Increased winter mortality from acute myocardial infarction and stroke: the effect of age. Journal of the American College of Cardiology. 1999;33(7):1916-9. Epub 1999/06/11.
20. Woodhouse PR, Khaw KT, Plummer M, Foley A, Meade TW. Seasonal variations of plasma fibrinogen and factor VII activity in the elderly: winter infections and death from cardiovascular disease. Lancet. 1994;343(8895):435-9. Epub 1994/02/19.