Title: Seasonal Variation of Vitamin D in Ischemic Stroke

Authors: Richa Giri, Rohit Rai, Rajendra Kumar Verma, Shivendra Verma

 DOI:  http://dx.doi.org/10.18535/jmscr/v4i2.76

Abstract

This study aimed to investigate the seasonal variation of serum vitamin D level in ischemic stroke patients. 217 patients with ischemic stroke were selected for analysis between ages 45 and 80 yrs admitted at our hospital from Jan 2014 to Dec 2015. Measurements of serum vitamin D concentration was made by electrochemiluminescence immunoassay. Confounding variables like diabetes, hypertension, smoking, alcohol, tobacco, dyslipidemia, BMI, CRP, S. uric acid, duration of sunlight exposure, prior history of drug intake or fracture and S. calcium were considered. 200 age and sex matched controls were taken. The mean serum level of vitamin D was 19.14 +/- 9.45 SD ng/mL.  Highest vitamin D levels were seen in the month of July and low levels were seen during August and September. Vitamin D levels varied according to duration of sunlight exposure and season in ischemic stroke patients.

Keywords-Vitamin D, cerebral infarction, seasonal variation

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