Title: A Study on Antibiotic Sensitivity Pattern in Biofilm Positive and Negative Isolates of Pseudomonas Aeruginosa Isolated From Clinical Samples
Authors: Sowmya Nasimuddin, Jeevan Malaiyan, Mohanakrishnan Kandaswamy, Priyadharshini Parthasarathy, Sumathi Gnanadesikan, Savitha S, Kamal Raj M
DOI: http://dx.doi.org/10.18535/jmscr/v4i3.38
Abstract
Pseudomonas aeruginosa, a potential hospital pathogen with the tendency to form biofilm and multidrug resistance. Our study is to observe the correlation between biofilm formation by Pseudomonas aeruginosa and an accelerated increase in frequency of multidrug resistance when compared to non-biofilm producers. A total of 100 isolates of Pseudomonas aeruginosa [Pus (59%), urine (21%), sputum (16%) and other samples (4%)] were taken for our study. Biofilm formations by tube method were found in 86 isolates (86%) with 85% (17/21) of the urinary isolates forming biofilm. Resistance to Carbapenam, Cephalosporins and other anti – Pseudomonal antibiotics were clearly observed to be more in biofilm producing isolates than non biofilm producers.
KEY WORDS: Pseudomonas aeruginosa, Biofilm, Tube method.
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