Title: Persistence and Cure Rates of Primary Hyperparathyroid Disease after Bilateral Neck Exploration (BNE)
Authors: Mohamed Zaky Azzam, Eman Zaki Azzam, Tarek Youssef Koraitum
DOI: http://dx.doi.org/10.18535/jmscr/v4i4.23
Abstract
Eighteen patients suffering from primary hyperparathyroid (PHPT) disease underwent BNE in Alexandria University Hospital in the last two years with the objective to estimate the accuracy of imaging in localizing the site of the disease and the efficacy of BNE in cure rates in these patients. Single gland disease (SGD) was found in 13 patients (72%) and multigland disease (MGD) in 5 patients (28%). In the 13 patients with SGD, the disease was confined to one of the lower parathyroid glands (5 in the right gland and 8 in the left one). During the period of regular postoperative follow up for six months, 15 patients achieved complete cure (83%) and 3 patients (17%) showed persistence of the disease. These three patients were having SGD; one of them the cause of persistence was carcinoma of the excised PT gland while in the other two the cause of persistence was activation of an occult adenoma in the other neighboring lower PT gland.
Keywords: PHPT, BNE, PTH, SGD, MGD.
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