Title: Efficacy of Magnetic Resonance Imaging in Diagnosis of Eclampsia with Clinical Correlation and Follow Up: A Prospective Study in A Tertiary Hospital
Authors: Dr Veena, Dr Shivani Gogi, Dr Anil Kumar, Dr Shanthi Sree, Dr Hanumath Prasad, Dr Sumithra
DOI: http://dx.doi.org/10.18535/jmscr/v4i9.92
Abstract
Aims and objectives: 1)To analyse the imaging features in eclampsia 2)To study the distribution and nature of cranial MRI findings in eclampsia. 3) To correlate the MRI findings with neurological symptoms and blood pressures.4) To predict the pathogenesis associated with abnormal MR imaging findings. 5) Clinical follow up to see for the recovery from neurological deficits.
Summary: In the present study, during the period of 12 months ,55 cases of eclampsia were evaluated with MRI brain.29 cases showed changes of Progressive Reversible Leuko Encephalopathy as T2 hyperintense signals with no restriction on DWI.
Conclusion: Cranial MRI is an important diagnostic tool in evaluation of intracerebral changes in cases with eclampsia. The posterior cerebral circulation is most commonly affected in cases of eclampsia.The posterior reversible encephalopathy lesions in eclampsia are reversible.
Keywords: Eclampsia, MRI(T2 and DWI),Progressive Reversible Leuko Encephalopathy.
References
1. Cunningham FG Macdonald PC, Grant NF. Hypertensive disorders of pregnancy. In: Cunningham FG Macdonald PC, Grant NF,eds. Williams” obstretics. 18th ed. Noerwalk, conn:Appleton&Lange, 1989 ; 653-694.
2. Lindheimer MD Katz Al. Preeclampsia: pathophysiology, diagnosis and manage-ment. Ann Rev Med 1989; 40:233-250.
3. Feske SK Spelling RA, Schwartz RB: Extensive reversible brain magnetic resonanace lesion in a patient with HELLP syndrome Neuroimaging 7: 247,1997.
4. Shah AK, Whitty JE. Brain MRI in peripartum seizures: usefulness of combined T2 and diffusion weighted MR imaging. J Neurol Sci. Jul 1 1999; 166(2):122-5.
5. Sengar AR, Gupta RK, Dhanuka AK, et al. MR imaging, MR angiography, and MR spectroscopy of the brain in eclampsia. AJNR AM J Neuroradiol. Sep 1997;18(8):1485-90.
6. Shah AK, Rajamani K, Whitty JE. Eclampsia : A Neurological perspective. J Neurol Sci. Aug 15 2008;271(1-2):158-67.
7. Chakravarty A, Chakrabarty S D. The neurology of eclampsia : some observations. Neurol India 2002;50:128.
8. OZGUR DEMIRTAS et al.
Cranial MR imaging with clinical correlation in preeclampsia and eclampsia.. Diagn Interv Radiol. 2005 Dec;11(4):189-94.
9. L. ELLWOOD J. MOODLEY P. CORR, J. "Cerebral magnetic resonance imaging in eclampsia: a series of 12 cases." Journal of Obstetrics and Gynaecology 18.5 (1998): 412-418.
10. Chang WN, Lui CC, Chang JM. CT and MRI findings of eclampsia and their correlation with neurologic symptoms. Zhonghua Yi Xue Za Zhi (Taipei). 1996; 57: 191-197.
11. Karuppannasamy, Divya et al. “Cortical Visual Loss in Posterior Reversible Encephalopathy Syndrome in Late Postpartum Eclampsia: Case Series. ”Indian Journal of Ophthalmology 62.5 (2014): 635–638. PMC. Web. 26 Sept. 2016.
12. Diego J. Covarrubias, Patrick H. Luetmer, and Norbert G. Campeau: Posterior Reversible Encephalopathy Syndrome: Prognostic Utility of Quantitative Diffusion-Weighted MR Images. AJNR Am J Neuroradiol June/July 2002, 23:1038–1048.