Title: Patterns of Distant Failure in Carcinoma Cervix- A Regional Cancer Centre Experience
Authors: Dr Sanjukta Padhi, Meher Papuji, Sahoo Bijayalaxmi, Mohanty Sulagna
DOI: https://dx.doi.org/10.18535/jmscr/v4i10.52
Abstract
Background: Cervical cancer is the most common malignancy among Indian females and is the leading cause of death. Patients with locally advanced cervical cancer after concurrent chemo radiation distant failure occur in many cases.
Aim: To study the age distribution, clinical profile, sites, patterns, & duration of development distant failure in carcinoma cervix after completion of primary treatment.
Materials: Retrospective study from the treatment records of patients of carcinoma cervix undergoing treatment at AHRCC. From January 2013 to June 2016, 91 patients of metastatic carcinoma cervix were selected & analysed retrospectively.
Result: Majority of patients were from 5th and 6th decade followed by 7th decade. Most of them were in stage IIIB followed by stage II. Squamous cell histology was the most common entity. Commonly presented with non-regional nodal metastases out of which para-aortic lymph node metastases predominates. Following nodal metastases lungs was the second most site. Liver, bone and brain metastases were also seen. Most of the patients presented with metastasis within a period of 2 years from initial treatment time.
Conclusion: Distant failure in carcinoma cervix depends upon the initial stage, age of presentation and histological findings. Though cervical carcinoma frequently spreads to the para-aortic nodes, lungs, liver and other uncommon sites are also reported. It necessitates a stringent follow up during period of first two years.
Keywords: Carcinoma Cervix, Distant Metastasis.
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