INTRODUCTION: Seizures are common disorders found all over the world and are encountered frequently during medical practice in variety of settings.

Etiological spectrum of acute symptomatic seizures in developing countries is different from developed countries. The major etiological risk factors were central nervous system (CNS) infections (32%), metabolic disorders (32%) and cerebrovascular diseases (21%).1 Presently CNS infections like malaria, meningitis, tuberculosis, Human Immunodeficiency Virus (HIV) and neurocysticercosis account for significant number of cases in developing countries.² Since these infections vary from region to region; etiology of seizure may also vary from region to region.

AIMS AND OBJECTIVE: (1) To study distribution of  CNS infection as a cause of new onset seizure.

(2)To study types of CNS tuberculosis which cause new onset seizure.

MATRIALS AND METHODS: 100 patients admitted with new onset seizures from the hospital attached to  S. S. Medical College, REWA and study conducted from  july 2014 to October 2015.Seizure history was taken from eyewitness  and patient and clinical examination and routine investigation  done,with special investigation like CT, MRI, EEG in selected cases.Result was analysed statically and mean  and standard deviation was calculated.

RESULT: CNS infection constitute major portion of new onset seizure (31%).Out of these Neurocysticer-cosis (32.2%),tuberculosis (25.8%),bacterial meningitis(16.1%), cerebral malaria(16.1%),viral meningitis and encephalitis (9.67%).Tubercular infection constitute tuberculoma (62.5%), tubercular meningitis (25%), and tubercular meningoencephalitis(12.5%) cases.

CONCLUSION: CNS infection (31%) were the leading cause of seizure and among these majority of seizures were because of Neurocysticercosis. Also Neurocysticercosis can be easily prevented by maintaining good hygiene, sanitary conditions and avoiding open defecation.

KEYWORDS: CNS infection, seizure, tuberculosis.