Title: Basaloid Cloacogenic Carcinoma of Anal Canal Showing Complete Response to Chemoradiotherapy: A Rare Case with Review of Literature

Authors: Kaushal Deep Singh, Farheen Shahma

 DOI:  https://dx.doi.org/10.18535/jmscr/v4i11.106

Abstract

Cloacogenic carcinoma is a rare tumor originating from epithelium of the anal transition zone of embryonic residuals. It accounts for only 2%–3% of all neoplasm arising in the anorectal canal and has clinical and morphological characteristics that distinguish them from the ordinary varieties of adenocarcinoma and squamous cell carcinoma of the anorectum. We report here a case of a middle aged male who presented to us with history of altered bowel habits, pain during defecation, passage of fresh blood in stools and pruritus in anal region and on examination there was an ulcerative growth in the anal canal. The diagnosis of basaloid variety of cloacogenic carcinoma was made upon biopsy and histopathological examination. Patient was put on chemoradiation and responded well with complete disappearance of growth macroscopically and clinically but was then lost in follow-up.Owing to the paucity of published literature on this rare malignant tumor this case is being reported here.

Key Words: Cloacogenic carcinoma, basaloid, anal canal, chemoradiation, complete resolution.

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