Title: Kikuchi Disease Mimicking Tuberculosis: Case Report
Authors: Dr Omar Sami Basubrain, Dr Ebtehal Matar, Dr Enas Alahmadi, Dr Hassnah Omar Dammas
DOI: https://dx.doi.org/10.18535/jmscr/v4i11.91
Abstract
Kikuchi-Fujimoto Disease (KFD) is a rare cause of lymphadenopathy due to necrotizing lymphadenitis. It is relevant in Asia; however, many areas in the world report such diagnosis. This disease usually affects females at 20-40 year of age. KFD often manifest as cervical lymphadenopathy. It is a self-limited disease with a period ranging from few weeks to 6 months. The clinical picture is quite close to systemic lupus erythematosus (SLE), lymphoma or tuberculosis. We report one of three cases of KFD diagnosed in our hospital over a period of three years. Our patient is a 27-year-old man of African ethnicity. We will discuss the presenting symptoms, our differential diagnosis, radiographic findings, and pathology of this case, and we review the literature to assist physicians in diagnosing this benign and uncommon entity.
Keywords- Kikuchi, Fujimoto, necrotizing granuloma, cervical lymphadenopathy, Histocytic lymphadenitis.
References
1. Chatterjee SS, Sengupta K, Mukhopadhyay P, Bandyopadhyay D, Chaudhury SR. A case of Kikuchi-Fujimoto disease. Journal, Indian AcadClin Med. 2014;15(3–4):224–6.
2. Beider-Preston D, Pound C, Jurencak R. An atypical presentation of Kikuchi-Fujimoto Disease associated with a transient increase of lupus-specific autoantibodies: Case report and literature review. ClinExpRheumatol. 2011;29(2):455.
3. Ranabhat S, Tiwari M, Kshetri J, Maharjan S, Osti BP. An uncommon presentation of Kikuchi-Fujimoto disease: a case report with literature review. BMC Res Notes [Internet]. BioMed Central; 2015;8:4–7. Available from: "http://dx.doi.org/10.1186/s13104-015-1460-x
4. Kumar A, Chhabria MS, Bg C. Case Report Kikuchi-Fujimoto Disease: A rare cause of PUO - Case Report. 2016;(2):112–4.
5. P DR, H SK, V DN. Kikuchi-Fujimoto disease in a 11-year male child: A Rare Case Report and Review of literature. 2015;4(1).
6. Kahn MQ. Kikuchi-Fujimoto Disease (KFD): A Case Report. Pacific J Sci Technol. 2015;16(2):216–8.
7. Deaver D, Naghashpour M, Sokol L. Kikuchi-Fujimoto disease in the Unites States: Three case reports and review of the literature. Mediterr J Hematol Infect Dis. 2014;6(1).
8. Bennie MJ, Bowles KM, Rankin SC. Necrotizing cervical lymphadenopathy caused by Kikuchi-Fujimoto disease. Br J Radiol [Internet]. 2003 Sep;76(909):656–8.
9. Jaudah Al-Maghrabi and Hassan Kanaan. Histiocytic necrotising lymphadenitis (Kikuchi- Fujimoto disease) in Saudi Arabia: clinicopathology and immunohistochemistry. Ann Saudi Med 2005;25(4):319-323