Title: Hypertriglyceridemia in Pregnancy Induced Hypertension
Authors: Dr V. Breetha, Dr K. Lavanya Kumari, Dr S.Sethupathy
DOI: https://dx.doi.org/10.18535/jmscr/v4i11.31
Abstract
AIM: Pregnancy-induced hypertension (PIH) is a common medical complication of pregnancy with a high incidence. Hormonal imbalance leading to altered lipid profile in serum is attributed to be one of the prime factors in etiopathogenesis of pregnancy-induced hypertension (PIH). So, the serum lipid profile in women with pregnancy induced hypertension and healthy pregnant women, in third trimester was evaluated in an attempt to study the etiopathogenesis and relationship of lipid levels to its complications, in the rural population attending our Medical College Hospital
METHODS: This is a case control study comprising of 50 normal and 50 PIH cases in their third trimester of pregnancy. The serum Triglycerides (TG), Total cholesterol (TC), HDL-cholesterol (HDL-C), very low density lipoprotein (VLDL) and LDL- cholesterol (LDL-C) were evaluated and analyzed by auto analyzer.
RESULTS: There was a significantly higher fasting triglycerides, total cholesterol, VLDL and LDL-C levels in PIH cases (P=<0.01), as compared to healthy pregnant women.
CONCLUSION: Elevated serum total cholesterol and LDL cholesterol observed in PIH cases indicates abnormal lipid status and further studies are required to find out the implications of this on etiopathogenesis of PIH and foetal outcome in these cases.
KEYWORDS: lipid profile, pregnancy-induced hypertension (PIH), Triglycerides (TG), Total cholesterol (TC), HDL-cholesterol (HDL-C),Very low density lipoprotein( VLDL) and LDL- cholesterol (LDL-C).
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