Title: A Comparative Study between Dexmedetomidine and Fentanyl as Intrathecal Adjuvants to Bupivacaine for Lower Abdominal Surgery
Authors: Dr Amit Pradhan, Dr Mahendra Kumar Nayak, Dr Tarangini Das, Dr Ranjeeta Mahapatra, Dr Debasis Mishra
DOI: https://dx.doi.org/10.18535/jmscr/v4i11.06
Abstract
Aims and Objectives: Many adjuvants have been used with local anaesthetics in spinal subarachnoid block for better intraoperative and prolonged postoperative analgesia. The aim of this study is to compare the effects of dexmedetomidine and fentanyl as intrathecal adjuvant to hyperbaric bupivacaine on the onset and duration of sensory and motor block in lower abdominal surgeries.
Materials and Method-Ninety patients of ASA status I and II posted for lower abdominal surgery were randomly divided into two groups. Group D was administered hyperbaric bupivacaine 2.5ml + dexmedetomidine 5µg in 0.5 ml normal saline and group F was administered hyperbaric bupivacaine 2.5ml + fentanyl 25 µg in 0.5 ml normal saline . Duration and quality of sensory and motor block were assessed.
Results-Sensory and motor block in group D patients were longer than group F patients. Time taken for sensory blockade regression to S2 level was longer in D(396.67±24.12 min) group than F(190.60±26.12min) group which was statistically significant. Time taken for motor block regression to bromage 0 is longer in D(388.5±21.24min) group than F(134.8±19.76min) group which was also statistically significant.
Conclusion- Intrathecal dexmedetomidine when added as adjuvant to bupivacaine heavy (0.5%) provided better and prolonged analgesia in comparison to intrathecal fentanyl.
Keyword- Fentanyl, Bupivacaine, Intrathecal, Dexmedetomidine.
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