Title: Colorectal Carcinoma: Histopathological Analysis and Changing Trends in Various Parameters
Authors: Gauri Munjal, Kausalya Sahu K, Hema Kini, Radha Pai R, Jyoti Kini R, Pooja Suresh K
DOI: https://dx.doi.org/10.18535/jmscr/v4i12.84
Abstract
Colorectal cancer (CRC) is one of the major causes of morbidity and mortality world over. The aim of the present study was to analyse CRC according to age, sex, site, grade, stage and other important parameters and to determine the association of anatomical distribution, grade, stage of the tumor with the age of the patient. A cross sectional study was conducted on 100 resected specimens of CRC from January 2011 to July 2015 in our department of Pathology. All the cases were reviewed and the histopathological findings were recorded. The results were analysed using Chi square value (c2) and Fischer test. In our study, 100 cases of CRC were taken. The mean age at presentation was 57 years with male preponderance (64%). Colonic tumors were seen in 52% cases as compared to rectal tumors in 29% cases and rectosigmoidin 10% cases. Majority of the tumors were moderately differentiated (46%) and 41% were of TNM stage II. The analysis also revealed a statistically significant correlation between subsite, tumor grade and the age of the patient. Our results indicated an increase in the incidence of colonic tumors as compared to rectal tumors in all the age groups which can have an important clinical implication in selection of screening methods.
Keywords: Age, anatomic distribution, colorectal carcinoma, grade.
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