Title: Congenital Tuberculosis -A Rare Form of Tuberculosis

Authors: Dr Garima Biyani, Dr Syed M Azad, Dr Hriday De, Dr Rohit Kapoor

 DOI:  https://dx.doi.org/10.18535/jmscr/v4i12.73

Abstract

Congenital tuberculosis is a rare but fatal condition if left untreated. Considering the high incidence of maternal TB, cases of congenital TB have been largely under-reported. This may be because TB in the neonate more often has nonspecific or unusual presentations and their mothers are seldom symptomatic. In the absence of an associated history of maternal TB, it is difficult to diagnose clinically and commence timely treatment. This is the case report of infant with congenital tuberculosis with secondary bacterial infection which is diagnosed very early at the age of 1 month and treated accordingly with ATD and antibiotics. Our case also highlights the importance of taking a detailed history from patients.

References

1.      Connolly M, Nunn P. Women and tuberculosis. World Health Stat Q. 1996;49:115–19.

2.      Cantwell MF, Sehab ZM, Costello AM, Sands L, Green WF, Ewing EP et al. Congenital tuberculosis. N Engl J Med 1994; 330:1051-1054.| Article | PubMed| ChemPort |

3.      Hassan G, Qureshi W, Kadri SM. Congenital tuberculosis: mini review. JK Sci 2006; 8: 193–194.

4.      Adhikari M, Pillay T, Pillay DG. Tuberculosis in the newborn: an emerging disease. Pediatr Infect Dis J 1997;16: 1108-1112.| Article | PubMed | ChemPort |

5.      Singh M, Kothur K, Dayal D, Kusuma S. Perinatal tuberculosis: a case series. J Trop Pediatr 2007; 53: 135–138. | Article | PubMed |

6.      Hageman J, Shulman S, Schreiber M, Luck S, Yogev R. Congenital tuberculosis: critical reappraisal of clinical findings and diagnostic procedures. Pediatrics 1980; 66: 980–984. | PubMed | ChemPort |

7.      Bate TW, Sinclair RE, Robinson MJ. Neonatal tuberculosis. Arch Dis Child. 1986;61:512–14

8.      Vijayasekaran D, Kumar RA, Gowrishankar NC, Nedunchelian K, Sethuraman S. Mantoux and contact positivity in tuberculosis. Indian J Pediatr. 2006;73:989–93.

9.      Smith KC. Congenital tuberculosis: a rare manifestation of a common infection. Current Opin Infec Dis. 2002;15:269–7

10.  Parakh A, Saxena R, Thapa R, Sethi GR, Jain S. Perinatal tuberculosis: four cases and use of bronchoalveolar lavage. Ann Trop Paediatr. 2011;31:75–80.

11.  Balasubramanian S, Shivram R, Padma-sani LN, Nagaraju. Congenital tubercul-osis. Indian J Pediatr. 1999; 66:148–50.

12.  Thapa R, Mallick D, Biswas B. Perinatal malaria and tuberculosis co-infection: a case report. Int J Infect Dis. 2010;14:e254–6.

13.  Wanjari K, Mathur M, Baradkar VP, Kumar S. Congenital tuberculosis with candidal sepsis in a neonate. Indian J Pathol Microbiol. 2008;51:289–91.

14.  Das A, Arora J, Rana T, Porwal C, Kaushik A, Gaur G, et al.Congenital tuberculosis: the value of laboratory investigations in diagnosis. Ann Trop Paediatr. 2008;28:137–41.

15.  Bhat RY, Rao A, Altaf, Prakashini K.  An evolved diagnosis of congenital tuberculosis in a very low birth weight premature neonate. Int J Tuberc Lung Dis. 2008;12:344–5.

16.  Premkumar M, Anumakonda V, Cormican L, Ruiz G, Greenough A. Feeding intolerance due to connatal tuberculosis in a prematurely born infant. Eur J Pediatr. 2008;167:955–6.

17.  Singh M, Kothur K, Dayal D, Kusuma S. Perinatal tuberculosis a case series. J Trop Pediatr. 2007;53:135–8.

18.  Surve TY, Malkani M, Mhatre A, Samdani VP. Congenital TB associated with asymptomatic maternal endometrial TB. Trop Doct. 2006;36:59–61.

19.  Kumar R, Gupta N, Sabharwal A, Shalini. Congenital tuberculosis. Indian J Pediatr. 2005;72:631–3.

20.  Grover SB, Pati NK, Mehta R, Mahajan H. Congenital spine tuberculosis: early diagnosis by imaging studies. Am J Perinatol. 2003;20:147–52.

21.  Ray M, Dixit A, Vaipei K, Singhi PD. Congenital tuberculosis. Indian Pediatr. 2002;39:1167–8.

22.  Pal P, Ghosh A. Congenital tuberculosis: late manifestation of the maternal infec-tion. Indian J Pediatr. 2008;75:516–18.

Corresponding Author

Dr Garima Biyani

ICH, Kolkata

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