Multicentric Reticulohistiocytosis, A Rare Cause of Polyarthritis with Skin Manifestations in Paediatric Age Group: A Case Report

Title: Multicentric Reticulohistiocytosis, A Rare Cause of Polyarthritis with Skin Manifestations in Paediatric Age Group: A Case Report

Authors: Dr Hriday De, Dr Mandira Roy, Dr Priyankar Pal, Dr Prabhas Prasun Giri, Dr Deepshikha Mishra

DOI: https://dx.doi.org/10.18535/jmscr/v4i12.62

Abstract

Backgound: Multicentric reticulohistiocytosis is a rare proliferative histiocytic disease of unknown etiology with potentially disabling nature. Primary manifestations are involvement of skin as paulonodular leisons and arthritis . The articular destruction can lead to permanent joint deformities.

Case Presentation: Our patient is a 11 year old boy presented with polyarthritis and reddish- brown papulonodular cutaneous lesions. The diagnosis of multicentric reticulohistiocytosis was confirmed by histopathological examination of skin nodules that was further substantiated by immunohistochemistry. The boy responded with oral corticosteroids and subcutaneous methotrexate injection.

Conclusion: Though Multicentric reticulohistiocytosis (MRH) is a rare condition in pediatric patients, but it is with potentially disabling nature, timely diagnosis and treatment with immunosuppressant can controll this disease process.

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Corresponding Author

Dr Hriday De

Institute of Child Health, Kolkata

Postal address: Institute of Child Health, 11 Dr. Biresh Guha Street, Kolkata -700017, Country- India

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