Title: Profile of Adverse Drug Reactions in TB Patients Taking ATT
Authors: Dr Aashutosh Asati, Dr Manoj Indurkar
DOI: https://dx.doi.org/10.18535/jmscr/v4i12.48
Abstract
INTRODUCTION- Tuberculosis treatment need more than one drug combination to eradicate tuberculosis bacteria.2 The use of multidrug regimens has been associated with increased incidence of adverse drug reactions of anti-tubercular drugs. Hence, there is a need to monitor the adverse effects of antitubercular drugs in a hospital set up.
METHODOLOGY- Information on any past or current occurrence of adverse effects due to the ATT drugs being administered to the patients was collected. Frequency distribution tables were prepared from the collected data.
RESULTS AND DISCUSSION- In our study Gastrointestinal symptoms like Anorexia, Vomiting, Nausea, abdominal pain were the most commonly reported ADRs followed by headache and tingling and burning sensation in hands and feet. Similar adverse effects were reported in other studies. Adverse drug reactions were more frequently and more severely reported among females and elderly patients (>60yrs).
CONCLUSION- Adverse drug reactions among patients taking anti tubercular treatment is common, So identification of such adverse effect and prompt management will definitely be very helpful for a successful anti tubercular chemotherapy.
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