Title: Clinical Profile of Fever with Thrombocytopenia in Tertiary Hospital, Jhalawar Medical College
Authors: Dr Raghunandan Meena, Dr Naresh Kumar Meena
DOI: https://dx.doi.org/10.18535/jmscr/v4i12.39
Introduction- Fever with thrombocytopenia has become the commonest presenting problem in the medical wards. Various infectious causes are there for fever with thrombocytopenia. It is necessary to know the cause, which will be useful to give proper treatment to the patient. Aims: The object is to determine possible infective etiology for fever with thrombocytopenia and to study the presentation and complications of thrombocytopenia Material and Methods: This was a prospective study conducted on 100 patients with fever and thrombocytopenia, admitted in department of medicine and paediatrics, Jhalawar Medical College, Jhalawar Results-100 patients of fever with thrombocytopenia Dengue (43%) was the commonest cause of fever thrombocytopenia followed by Malaria (41%) and other viral fever. Maximum percent of bleeding seen at 20000 to 50000 cumm platelet count. Out of 100 patients 12 patients showed bleeding manifestations. The Commonest form of bleeding manifestation was petechiae in 10 patients followed by GI Bleed in 2%. We conclude that the febrile illness patients should be investigated for platelet count whether they have bleeding manifestations or not. Strong probability of dengue fever or other common causes like malaria, viral fever and enteric fever should be kept in mind in any case of fever. Keywords- Fever, thrombocytopenia, Malaria, Bleeding manifestation. 1. Mackowiak, P.A. “History of Clinical Thermometry: In Fever: basic mechanisms and management”. (ed. Mackowiack P.A), New York, LippincottRaven Publishers, Philadeplphia, 1997 ; pp1-10. 2. Dinarello, C.A. “Cytokines as Endogenous Pyrogens: In Fever: basic mechanisms and management”. (ed. Mackowiack P.A), New York, Lippincott-Raven Publishers, Philadelphia, 1997; pp87-116. 3. Woodward T.E. “The Fever Pattern as a Diagnostic Aid: In Fever: basic mechanisms and management”. (ed. Mackowiack P.A), New York, Lippincott -Raven Publishers, Philadelphia, 1997: pp215-235. 4. Handian RI. Bleeding and thrombosis. Chapter 62, In: Harrison principles of internal medicine, 15th Ed. Vol.1, Edt. Braunwald et al, USA: McGraw Hill, 2001. pp358. 5. Firkin, Chesterman, Penangtion Rush. Edt., Haemorrhagic disorders; Capillary and platelet defects Chapter -14, In: Degruchy’s Clinical haematology in Medical practice, 5th Ed; Oxford Black well science, 1989: pp360.) 6. George JN, Aizvi MA. Thrombocytopenia. Chapter- 117, In: Williams haematology, 6th Ed, Edt. Ernest Beufler et al, USA: McGraw Hill, 2001 pp1501. 7. Risdall RJ, Brunning RD, Hernandez JL, Gordon DH et al. Bacterial associated haemophagocytic syndrome. Cancer, 1984 Dec. 15; 54(12): 2968- 72. 8. Lohitashwa SB, Vishwanath BM, Srinivas G A Study of Clinical and Lab Profile of Fever with Thrombocytopenia JAPI volume 57 March 2009. 9. Nair PS, Jain A, Khanduri U, Kumar V. “A study of fever associated with thrombocytopenia‟‟. JAPI,2003 Dec 51 : 1173 10. Gandhi Amita,Akholkar Pankaj,clinical and laboratory evaluation of patients with febrile thrombocytopenia,NJMR 2015;5(1):43-6. 11. Nikalje Anand1 , Talib S.H.2 , Pagar Bhushan3 , Patil Sumit4 , Patil Piyush5 , Kurhade Aniket Clinical Outcomes of Patients Presenting As Fever with Thrombocytopenia in Marathwada Region International Journal of Science and Research (IJSR), Volume 5 Issue 2, February 2016 12. Raikar Shankar, kamdar Panna.clinical and laboratory evaluation of patients with fever with thrombocytopenia, Indian j of clinical practice, vol 24,no.4,sept 2013:360-3. Dr Naresh Kumar C/o Deepak Kumar, OM Medical Store in front of SRG Hospital, Jhalawar (Rajasthan), Pin -326001 Email:- This email address is being protected from spambots. You need JavaScript enabled to view it., Contact:- 7597284435Abstract
References