Title: A rare case of Sclerosing stromal tumour with ascites and raised CA 125 mimicking primary ovarian malignancy

Authors: Dr Shahina P.K, Dr Resmi Rajeev, Dr Shameem K. Ummer Ali

 DOI: https://dx.doi.org/10.18535/jmscr/v14i02.02

Abstract

 

Sclerosing stromal tumour is a rare benign sex cord stromal tumour of ovary. A 16 year old female presented with menorrhagia & fever. MRI showed large welldefined heterogenous mass lesion of size 9x11x12cm in the lower abdomen and pelvic cavity. There was mild ascites and  serum CA 125 levels were elevated  which mimicked the possibility of primary ovarian malignancy . Staging laparotomy was done. Macroscopic examination showed an encapsulated solid mass.  Cut section showed grey white solid mass with glistening areas. Histopathological examination showed a neoplasm composed of alternating cellular and hypocellular areas and thin branching hemangiopericytoma like vessels. Immunohistochemical analysis showed positive results for Vimentin, SMA & calretinin. Inhibin, CK, CD 34 & Bcl2 were negative in tumour cells. A diagnosis of  Sclerosing stromal tumours was  given. About 8% ovarian tumours are sex cord stromal tumours and of these sclerosing stromal tumour compromises less than 5 %. Around 208 cases of SSTs are described in literature till now.(1)

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