Title:  Trichosporon inkin causing intraluminal conduit vegetation from Right ventricle to main Pulmonary artery extending till hilar branch pulmonary arteries-treated with Surgery followed by antifungal medications - A case report

Authors: Shweta Sharma, Smruti Ranjan Mohanty, Sweta Shah

 DOI: https://dx.doi.org/10.18535/jmscr/v13i09.03

Abstract

 

Introduction

Trichosporon species are basidiomycetous yeast like anamorphic organisms that are widely distributed in nature and found predominantly in tropical and temperate areas. This fungal species is a part of commensal flora of skin and mucosa occasionally. It causes white piedra i.e the superficial infection of the hairs, invasive infections are rare and seen mostly in immunocompromised hosts1. Here we are reporting a case of RV-PA conduit infection in an immunocompetent child.

Observation

A 2 year old child who is a case of Tetralogy of fallot and had undergone RVOT stenting in his initial one month of life had come for Intracardiac repair. CT pulmonary Angiogram was done and the decision to go ahead with ICR and a RV-PA conduit was undertaken. Child underwent ICR with 14 mm e-PTFE RV to PA conduit placement on 27 th November 2024, Child had an uneventful post op course and was discharged .The child was lost to follow up and he came with the complaints of fever for 15 days for which he was already admitted for a period of 7 days and had received antibiotics to which he has not responded and hence was referred to us. A 2D-ECHO was done which had shown a suspicion of RV to PA conduit large vegetation with the RVOT gradient of 120 mmHg, mild conduit regurgitation with good flows in branch PAs and moderate TR.A CT pulmonary angiography scan was done to confirm the presence of large vegetation in the conduit. antibiotics   amikacin,  vancomycin,and  mphotericin B were started and the decision to go ahead with the surgery to remove vegetations and conduit replacement was taken

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