Title: An enigmatic presentation of concurrent papillary carcinoma in thyroid and thyroglossal cyst: a dual challenge
Authors: Dr Fida Harish A T, Dr R Balaji, Dr Sriprakash Duraiswamy
DOI: https://dx.doi.org/10.18535/jmscr/v13i05.11
Abstract
In the realm of thyroid malignancies, the coexistence of concurrent papillary carcinoma in both the thyroid gland and thyroglossal cyst presents a unique and intriguing clinical scenario. We present an unusual case of 40 year old female with these dual papillary carcinoma who underwent total thyroidectomy with thyroglossal cyst excision with left selective neck dissection followed by I-131 radiation ablation therapy. On follow up, the patient was found to have papillary carcinoma cervical metastasis on the contralateral side 2 months later and was treated by right functional neck dissection. Through this case report, we aim to contribute to the complexities associated with such coexisting papillary carcinomas, emphasizing the need for comprehensive evaluation and tailored therapeutic approaches in managing these intricate cases.
Keywords: papillary carcinoma, thyroid, thyroglossal duct cyst.
References
- Gomez-Alvarez LR, Trevino-Lozano MA et al. Papillary thyroid carcinoma from a thyroglossal cyst: case series. J Surg Case Rep. Feb 2022; 2022(2): 1-4.
- Fernandez JF, Ordonez NG, Schultz PN, Samaan NA, Hickey RC. Thyroglossal duct carcinoma. Surgery 1991;110:928-34.
- Vera-Sempere F, Tur J, Jaén J, Perolada JM, Morera C. Papillary thyroid carcinoma arising in the wall of a thyroglossal duct cyst. Acta Otorhinolaryngol Belg. 1998;52:49–54.
- Liaw J, Cochran E, Wilson MN. Primary Papillary Thyroid cancer of a Thyroglossal duct cyst. Ear, Nose & Throat Journal. 2019;98(3):136-138.
- Balalaa N, Megahed M, Ashari MA, Branicki F. Thyroglossal duct cyst papillary carcinoma. Case Rep Oncol. 2011 Jan 29;4(1):39-43.
- Iftikhar H, Ikram M, Nathaniel KR, Muhammad AY. Papillary Thyroid Carcinoma within Thyroglossal Duct Cyst: Case series and Literature Review. Introduction Arch Otorhinolaryngol. 2018 Jul; 22(3): 253-255.
- Gebbia, V., Di Gregorio, C. & Attard, M. Thyroglossal duct cyst carcinoma with concurrent thyroid carcinoma: a case report. J Med Case Reports. 2, 132 (2008).
- Hakeem AH, Hakeem IH, Pradhan SA, Hathiram B et al. Papillary carcinoma in a thyroglossal duct cyst with concurrent thyroid microcarcinoma and neck nodal metastasis. Indian J Surg Oncol. Sep 2013; 4(3):229–232.
- Karbek B et al. Coexistence of thyroglossal duct papillary carcinoma and thyroid papillary microcarcinoma. Turk Jem 2013; 17: 127-128.
- Mobini J, Krouse TB, Klinghoffer JF. Squamous cell carcinoma arising in a thyroglossal duct cyst. Am Surg 1974;40:290–294.
- LiVolsi VA, Perzin KH, Savetsky L. Carcinoma arising in median ectopic thyroid. Cancer 34:1974;1303–1315.
- O’Connell M, Grixti M, Harmer C. Thyroglossal duct carcinoma: presentation and management including eight cases reports. Clin Oncol. 1998;10:186–190.
