Title: Substituting Brands: A Case Study of DEKSEL an “Evidence-based Formulation”
Authors: Sangeeta Choudhury, Harsh Chaturvedi
DOI: https://dx.doi.org/10.18535/jmscr/v13i01.08
Abstract
Brand substitution should not be encouraged because of various reasons like drug content, formulation stability, difficulty in establishing bio-equivalence, and above all patient and prescriber familiarity with a specific brand etc., as this all may have a bearing on treatment outcome. A wide range of variation is seen as far as drug content of a formulation is concerned, in the Indian market. This wide variation in drug content might result in either inefficacy or toxicity with the drug/ formulation. In this review we are going to discuss about the necessity of using the prescribed brand and not substituting them with others with some examples.
Keywords: Brand, Cost, Efficacy, Safety, Substitution, Generic.
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