Nitrofurantoin is a synthetic nitrofuran antimicrobial commonly used for the treatment and prevention of recurrent urinary tract infections (UTIs). Although rare nitrofurantoin can cause acute and chronic lung diseases. We report the case of an 81-year-old woman diagnosed with interstitial lung disease (ILD) due to long-term use of Nitrofurantoin for UTI prophylaxis. Despite widespread lung parenchymal changes in the form of fibrosis and ground glass opacities, she responded very well to corticosteroids. This case report highlights the importance of early recognition and favorable response to corticosteroids in nitrofurantoin-induced ILD.

Keywords: Nitrofurantoin, Lung Diseases, Interstitial Fibrosis, Corticosteroid.

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Harikrishnan Puliassery