Title: Hypothyroidism in Pregnancy: A Prevalence study in a Rural Medical College Hospital in North East Bihar
Authors: Nehanjali Kumari, Swapan Kumar Kundu, Soumyajyoti Kundu
DOI: https://dx.doi.org/10.18535/jmscr/v11i4.02
Abstract
Hypothyroidism, especially subclinical Hypothyroidism, affects 3-5% of pregnant mothers. Beta-Human chorionic gonadotropin causes thyroid stimulation since the first trimester. This cross sectional, descriptive, observational study was conducted on 900 mothers in OBGYN dept. of MGM Medical College, Kishanganj for 2 years to find out its prevalence. The prevalence of hypothyroidism was found to be 4.89% (n=44) with subclinical hypothyroidism being 4.11% (n=37) and overt hypothyroidism being 0.78% (n=7). The prevalence of anaemia, hypertension, preeclampsia and gestational diabetes was also found to be statistically significant.
Keywords: Hypothyroidism, Hyperthyroidism, Subclinical, TSH, Prevalence.
References
- Soldin OP, Tractenberg RE, Hollowell JG, et Trimester-specific changes in maternal thyroid hormone, thyrotropin, and thyroglobulin concentrations during gestation: trends and associations across trimesters in iodine sufficiency. Thyroid.2004; 14:1084-1090.
- Pop VJ, Brouwers EP, Vader HL, Vulsma T, van Baar AL, de Vijlder JJ 2003 Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow up Clin Endocrinol (Oxf) 59:282-288.
- Casey BM, Dashe JS, Wells CE, Mcintire DD, Byrd W, Leveno KJ, Cunningham FG2005 Subclinical hypothyroidism and pregnancy Obstet Gyneco/105:239-245.
- Porterfield SP, Hendrich CE. The role of thyroid hormone in prenatal and neonatal neurological development- current Endocrn Review.1993; 14:94-106.
- Taliadouros GS, Canfield RE et al, Thyroid stimulating activity of chorionic gonadotrophin and J Clin Endo Meta. 1978; 47:855-860.
- McDougall IR et al. Hypothyroid women need more thyroxine when pregnant. J Fam 1995;41;238-240.
- Lao TT, Chin RKH, Swaminathan R, Lam YM. Maternal thyroid hormones and outcome of preeclamptic Br J Obstet Gynecol 1990; 97: 71-74.
- Khandakar MA, Ali MS, Kahtun Thyroid status of normal pregnant women in Dhaka City. Mymensingh Med J 2002; 11: 1-5.
- Bankowska EM, Pawlowska A, Leibschang Thyroid function in pregnant women with pregnancy induced hypertension. Ginekol Pol 2003; 74: 1044-1048.
- Das C, Sahana PK, Sengupta N, Giri D, Roy M, Mukhopadhyay Etiology of anemia in primary hypothyroid subjects in a tertiary care centerin Eastern India. Indian J Endocr Metab 2012;16: S361-3.
- Morreale de Escobar G, Calvo R, Obregon MJ, Escobar del Rey F 1990 Contribution of maternal thyroxine to foetal