Title: Serous endometrial intraepithelial carcinoma (SEIC) with metachronous umbilical cutaneous, pleural, and peritoneal metastases: Case report and literature review
Authors: Zainab Chatbi, Ayoub Aouragh, Hafsa Taheri, Hanane Saadi, Ahmend Mimouni
DOI: https://dx.doi.org/10.18535/jmscr/v11i3.14
Abstract
Serous endometrial intraepithelial carcinoma is most often confined to the uterus, having consequently a favorable prognosis. However, and although this lesion remains limited to the epithelium with no stromal invasion, many cases of extrauterine spread have been reported at time of diagnosis or in a metachronous way. In this work we report the case of a 58-years-old menopausal female with pure serous endometrial intraepithelial carcinoma revealed by vaginal bleeding and pelvic pain with no metastases at exploration. She has undergone total hysterectomy, bilateral salpingo-oophorectomy and bilateral iliac lymph nodes dissection. Six months later, the patient presented with metachronous pleural, peritoneal and cutaneous metastases.
Keywords: Serous endometrial intraepithelial carcinoma, metastatic disease, case report.
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