Title: A Study on Prevalence of Thyroid Disorders in Pregnancy and its Impact on Maternal and Fetal Outcomes in a Tertiary Care Centre in Villupuram

Authors: Rajeswari Anandhan, Chitra Devi vinayagam

 DOI: https://dx.doi.org/10.18535/jmscr/v11i2.28

Abstract

Thyroid disease is one of the most prevalent endocrine abnormalities discovered during pregnancy. It has been linked to poor maternal and fetal outcomes. The most common obstetric consequences related with thyroid abnormalities are abortion, preeclampsia, abruptio placenta, premature labor, and fetal issues such as prematurity, low birth weight, still birth, and perinatal mortality. To identify the prevalence of thyroid disorders in pregnancy and its impact in material and fetal outcomes. Prospective study was conducted for a period of one year from January 2020 to December 2020. A total of 600 participants were enrolled in the study. The mean age of participants in the case and control group were identified as 24.73 ± 3.72 years and 24.06 ± 3.31 years, respectively. TSH was between 4.21 - 10 mIU/ml in the majority of the participants in the case group with 35.14%, followed by 2.5 - 4.20 mIU/ml with 32.43%. Hyperthyroidism and hypothyroidism were identified with 1% and 5.17%, respectively.  Preeclampsia, spontaneous miscarriage was the pregnancy outcomes identified in most of the participants in the case group with 13.51% and 8.11%. The study reveals a significant prevalence of thyroid disorders, particularly hypothyroidism, underscoring the importance of including thyroid function testing in regular antenatal clinic screening. Thyroid dysfunction must be diagnosed and treated as soon as possible in order to minimize negative prenatal outcomes.

Keywords: Hypothyroidism, Thyrotrophin, Pregnancy and Iodine deficiency.

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Corresponding Author

Rajeswari Anandhan

Professor, Department of Obstetrics and Gynecology,

Government Villupuram Medical College and Hospital, Tamilnadu, India