Title: Metachronous occurrence of Squamous Cell Carcinoma of Hypopharynx in a case of Chronic Myeloid Leukaemia: A Case Report
Authors: Dr Dhara Patel, Dr Maitrik Mehta, Dr Ankita Parikh, Dr Akash Pandya, Dr Heena Rathod, Dr Tasneem Nalawala, Dr Siddharth Malukar, Dr Krishna Prajapati
DOI: https://dx.doi.org/10.18535/jmscr/v11i2.11
Abstract
Chronic Myeloid Leukaemiais a neoplasm originating from malignant transformation of pluripotent hematopoietic stem cells. It occurs in adults and characterised by various phases. CML diagnosed at chronic phase treated with chemotherapy will lead to improved survival and life expectancy. Which in turn increases the chances of second malignancy. Secondary malignancies are most commonly squamous cell carcinoma of skin and aero-digestive tract. The secondary malignancy arising in case of leukaemia is aggressive in nature and has more chances of recurrence. Squamous cell carcinoma of larynx and hypopharynx are rarest. Herein, we report a case of Squamous cell carcinoma of Hypopharynx presented as a secondary malignancy in a primary underlying Chronic Myeloid Leukaemia.
Keywords: Squamous cell carcinoma, Hypopharynx, Chronic Myeloid Leukaemia, Radiation therapy, Secondary malignancy.
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