Title: Eccrine Angiomatous Hamartoma- A Rare Clinical and Histopathological Presentation
Authors: Dr Nelishka Gomes, Dr Varsha Shailendra Munj, Dr Dattaraj Budkule, Dr Chitralekha Thenge
DOI: https://dx.doi.org/10.18535/jmscr/v10i7.05
Abstract
Background: Eccrine Angiomatous Hamartoma is a vascular lesion of the skin. It is a rare benign tumor characterized by proliferation of eccrine and vascular components.
Case Details: We present an interesting case of 7 year old male who had a plaque like tumor present since birth over the heel of left leg which was gradually progressing to form a nodular swelling histopathological examination consist of proliferation of hyperplastic eccrine glands with dilated capillaries .the overlying epidermis showed marked verrucous changes which are reported in only a few cases of Eccrine Angiomatous Hamartoma .
Conclusion: Eccrine Angiomatous Hamartoma is a rare, slow growing benign tumor characterized by increased eccrine structures and capillaries. Epidermal change can be mistaken for verrucous skin lesion. Recognition of the lesion is important to decide on surgical intervention as simple excision is curative for a painful and aggressive tumor only.
Keywords: hyperkeratosis, parakeratosis , eccrine glands, verrucous , hamartoma.
References
- Larralde M, Bazzolo E, Boggio P, Abad ME, Santos Muñoz A. Eccrine angiomatous hamartoma: report of five congenital cases. Pediatr Dermatol. 2009; 26:316-9.
- García-Arpa M, Rodríguez-Vázquez M, Cortina P. Hamartoma angiomatoso ecrino. Piel. 2004;19:131-4.
- Foshee JB, Grau RH, Adelson DM, Crowson N. Eccrine angiomatous harmartoma in an infant. Pediatr Dermatol. 2006;23:365-8.
- Chien AJ, Asgari M, Argenyi ZB. Eccrine angiomatous hamartoma with elements of an arterio-venous malformation: a newly recognized variant. J Cutan Pathol. 2006; 33:433-6.
- Lee HW, Han SS, Kang J, Lee MW, Choi JH, Moon KC, et al. Multiple mucinous and lipomatous variant of eccrine angiomatous hamartoma associated with spindle cell hemangioma: a novel collision tumor?. J Cutan Pathol. 2006; 33:323-6.
- Hyman AB, Harris H, Brownstein MH. Eccrine angiomatous hamartoma. N Y State J Med 1968;68:2803-6.
- Shin J, Jang YH, Kim SC, Kim YC: Eccrine angiomatous hamartoma: a review of ten cases. Ann Dermatol 2013;25:208-212.
- Martinelli PT, Tschen JA. Eccrine angiomatous hamartoma: A case report and review of the literature. Cutis 2003; 71:449-55.
- Bastida J, Carretero G, Rivero MP, Borghi S, Domínguez J, Díaz C. Hamartoma ecrino angiomatoso. Actas Dermosifiliogr. 1997; 88:216-8
- Barco D, Baselga E, Alegre M, Curell R, Alomar A. Successful treatment of eccrine angiomatous hamartoma with botulinum toxin. Arch Dermatol. 2009;145:241-3.
- Nowakowski K, Dyduch G, Adult onset eccrine angiomatous hamartoma on the vulvaIndian J Dermatol 2012 51(7):840-41
- Zeller DJ, Goldman RL. Eccrine-pilar angiomatous hamartoma. Report of a unique case. Dermatologica. 1971; 143: 100–04.
- Pelle MT, Pride HB, Tyler WB. Eccrine angiomatous hamartoma. J Am Acad Dermatol. 2002;47:429–435.
- Laeng RH, Heilbrunner J, Itin PH. Late-onset eccrine angiomatous hamartoma: Clinical, histological and imaging findings. Dermatology. 2001;203:70–74.
- Cheong SH, Lim JY, Kim SY, Choi YW, Choi HY, Myung KB: A case of eccrine angiomatous hamartoma associated with verrucous hemangioma. Ann Dermatol 2009;21:304–307.
- Galan A, McNiff JM. Eccrine angiomatous hamartoma with features resembling verrucous hemangioma. J Cutan Pathol 2007;34 Suppl 1:68-70.
- Natarajan K, Rai R, Sundararajan V, Venkatchala S. Eccrine angiomatous hamartoma in an adult. Indian J Dermatol Venereol Leprol. 2009;75:193-4
- Laeng RH, Heilbrunner J, Itin PH. Late-onset eccrine angiomatous hamartoma: clinical, histological and imaging findings. Dermatology. 2001;203:70-4.