Title: Comparative Study of Efficacy of Platelet Rich Plasma Vs Superoxidised Solution in Treatment of Chronic Non- Healing Foot Ulcers
Authors: Dr Satish Kumar. R, Dr Venugopal. K, Dr Sharath. A
DOI: https://dx.doi.org/10.18535/jmscr/v10i4.04
Abstract
Background: Wounds and their management are fundamental in the practice of surgery. A chronic ulcer of the foot is a frequent condition and is a major health challenge and growing health problem all over the world.
Aims & Objectives: To compare the efficacy of Platelet rich plasma and Superoxidised solution in the management of chronic foot ulcers to observe: Wound disinfection, Rate of wound healing, Appearance of granulation tissue, Duration of hospital stay.
Materials: Randomized prospective comparative study of patients with chronic non healing foot ulcers admitted at our hospital from October 2018 to January 2020, patients were randomized into 2 groups- PRP and SOS with 25 patients in each group. Wound assessments done at regular intervals and various wound outcome variables compared. Statistical analysis of data done.
Results: In a study of 50 patients, most patients were in the age group of 51- 60years, 76% were diabetics and 78% were males. There was a rapid decrease in wound size in PRP group compared to SOS group at day 21, and earlier appearance of granulation and epithelialization in PRP group. The duration of hospital stay was almost equal in both groups.
Conclusion: This study shows more favorable results for PRP as compared to SOS in healing of chronic non healing foot ulcers which are highly statistically significant.
Keywords: Platelet Rich Plasma, Superoxidised Solution, Chronic non healing foot ulcers.
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