Title: Small Cell Esophageal Carcinoma with Merkel Cell Dysplasia: A Case Report
Authors: Anuradha Sekaran, Nafela A Siddiqui, Guduru Venkat Rao, Sundeep Lakhtakia, Duvvur Nageshwar Reddy
DOI: https://dx.doi.org/10.18535/jmscr/v10i3.08
Abstract
Neuroendocrine carcinoma (NEC) can rarely be associated with Merkel cell dysplasia. The clinical presentation is usually nonspecific and mild. Paraneoplastic MG is a rare autoimmune phenomenon related to esophageal NEC. We report a case of esophagus tumor having uncommon histology - (NEC) small cell type having Merkel cell dysplasia in the overlying epithelium, presenting as paraneoplastic Myasthenia gravis (MG). Neuro-muscular symptoms may be caused by paraneoplastic syndrome with underlying malignancy. The treatment options are different for esophagus squamous cell carcinoma and adenocarcinoma.
Keywords: Esophagus, Endoscopic ultrasound, Myasthenia crises, Merkel cell dysplasia, Neuroendocrine carcinoma.
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