Title: Significance of Frozen Section and Squash Cytology in Diagnosing C.N.S. Lesions and It’s Histopathological Correlation
Authors: Ambrish Kumar, Jini L Valooran, Khethmal P
DOI: https://dx.doi.org/10.18535/jmscr/v10i1.04
Abstract
Introduction: Intraoperative evaluation of lesions in central nervous system requires the correlation of clinical, radiological and histologic data and knowledge of clinicopathological entities and their common locations. The rapid diagnostic evaluation at Frozen Section may guide intraoperative management, which may be particularly important during open craniotomy. In addition, Frozen section allows for the appropriate triage of tissue for ancillary studies such as electron microscopy, microbiologic cultures, and frozen tissue storage. Intraoperatve consultations have become increasingly common in suspected cases of central nervous system. neoplasms. The study is designed to assess the accuracy of squash cytology and frozen section in diagnosing the CNS lesions on intra-operative biopsies in comparison to the gold standard paraffin embedded histopathological sections report of post operative specimens.
Methods: Diagnostic test evaluation. All the cases received from neurosurgery department for intraoperative diagnosis.
Results: Frozen section shows significant correlation with histopathology in CNS lesions
Conclusions: The role of Frozen Section in the intraoperative consultation is important. Our results show a high percentage of accuracy in the intraoperative diagnosis of CNS lesions.
Keywords: FS- Frozen section, SC- Squash cytology.
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