Title: A Prospective Study in Scrub Typhus Patients with Cardiac Manifestationsin- A Tertiary Care Center
Authors: Dr Divya Yeedulamudi, Dr K. Sudheer, Dr K. Mahendran
DOI: https://dx.doi.org/10.18535/jmscr/v9i11.21
Abstract
Introduction
Scrub typhus, a rickettsial infection caused by Orientia Tsutsugamushi
Typhus remains a substantially under-recognized disease entity, particularly in Asia, where up to 28% of malaria negative fevers can be attributed to rickettsial infections
The clinical manifestations of this disease range from sub-clinical disease to organ failure and death. Jaundice, renal failure, pneumonitis, ARDS, septic shock, myocarditis and meningoencephalitis are various known complications of this disease
In south East Asia alone, an estimated 1 million cases of scrub typhus occur yearly with approximately 50000-80000 deaths per year
Scrub typhus contributing to myocardial disease and death is not well established Myocarditis occurs due to disseminated endothelial infection of the small vessels or by secondary immune mediated mononuclear inflammation
Aim & Objectives
- To study the spectrum of cardiac manifestations in scrub typhus infection
- To evaluate the incidence of myocarditis
- To compare the outcome of scrub typhus patients with and without myocarditis
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