Volume 09 Issue 11 November 2021 Hits: 1749

Title: Correlation of Gallbladder Volume to Autonomic Neuropathy in Diabetics

Authors: Dr Patimalla Visala Bhavishya, Dr M .Madhusudhana Babu, MD, DM., Dr K. Sudheer, MD

DOI: https://dx.doi.org/10.18535/jmscr/v9i11.19

Introduction

Diabetes mellitus is most common endocrine disorder in humans characterized by chronic hyperglycemia due to defects in insulin secretion, insulin action or both
Prevalence of diabetes in adults in India is around8.9%
Complications of diabetes can be divided into acute & chronic complications
Acute complications include diabetic ketoacidosis, non ketotic hyperosmolar state, hypoglycemia.
Chronic complications can be divided into microvascular & macrovascular complication
Microvascular complications include eye disease (retinopathy, macularedema, cataracts), neuropathy (sensory & motor, autonomic), nephropathy
Macrovascular complications include coronary artery disease, peripheral artery disease, cerebrovascular disease
Diabetes is the commonest cause of autonomic peripheral A broad spectrum of symptoms affecting cardiovascular, gastrointestinal, urogenital, thermoregulatory, sudomotor & pupillomotor function canoccur
Gall bladder involvement in diabetic autonomic neuropathy occurs in form of increased gall bladder volume & impaired gall bladder contraction
Vagal parasympathetic fibers maintain gall bladder tone & influence it’s emptying
Hence gall bladder dysfunction may occur in autonomic neuropathy
Due to impaired contraction, stasis occurs and results in gall stone formation
Therefore gall bladder function should be routinely evaluated in diabetic patients