Ulcers pose a significant affliction to our health care system. The prevalence of chronic ulcers in Indian population is much higher than that reported in the Western population. The healing of ulcers is affected by multiple systemic and local factors, among which biofilm formation by the pathogens is a therapeutic challenge. The present study was undertaken for a period of 1 year from February 2015 to find out the biofilm production status of the isolates & to determine any association between biofilm production by the isolates and chronicity of the ulcer. In the present study, 66.9% of the total isolates from various types of ulcers were biofilm producers. ³⁷Gram positive bacteria were better biofilm producers in our study. Most frequent biofilm producers among Gram positives were Staphylococcus aureus & among Gram negatives it was Pseudomonas aeruginosa. 74% of isolates from ulcers of duration of >3 months were biofilm producers which was found to be a statistically significant association.

Keywords: ulcers, biofilm,  chronicity.

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