Abstract
Background: Endoscopic stent insertion is considered one of methods for palliation of malignant bile duct obstruction (MBDO).The aims of this study were to determine clinical characteristics that have the greatest adverse impact on quality of life in patients with malignant biliary obstruction, and to quantify changes in the quality of life of patients with malignantbiliary obstruction after successful decompression with a plastic stent.
Patients and Methods: Patients undergoing endoscopic retrograde cholangiopancreatography for MBDO completed the Functional Assessment of Cancer Therapy-General questionnaire at baseline, at 1 month after stent insertion and was used to quantify quality of life.
References
- Jemal A, Thomas A, Murray T, et al. Cancer statistics 2002.CA Cancer J Clin. 2002; 52:23–47.
- Lowy AM. From bad to worse: prognostic factors in pancreatic cancer. Ann Surg Oncol. 2004;11:117–118.
- Lowenfels AB, Maisonneuve P, Boyle P. Epidemiology of pancreatic cancer. In: Howard J, Idezuki Y, Ihse I, et al, eds. Surgical Diseases of the Pancreas. 3rd ed. Baltimore: Lippincott Williams & Wilkins; 1998:433–439
- Warshaw AL, Fernandez-del Castillo C. Pancreatic Carcinoma. N Engl J Med 1992; 326:455-465.
- Smith AC, Dowsett JF, Russell RC. Randomized trial of endoscopic stenting vs. surgical bypass in malignant bile duct obstruction. Lancet 1995: 344:1655-1660
- Linchtenstein DR, Carr-Locke DL. Endoscopic palliation of unresectable pancreatic carcinoma. Surg Clin North Am 1995; 75:969-988.
- Michael J. Levy, Todd H. Baron, Christopher J. et. al. Clinical Gastroenterology and Hepatology 2004; 2:273-285.
- Ballinger AB, McHugh M, Catnach SM, et al. Symptom reliefand quality of life after stenting for malignant bile duct obstruction. Gut. 1994;35:467–470.
- Pereira-Lima JC, Jakobs R, Maier M, et al. Endoscopicstenting in obstructive jaundice due to liver metastases: does ithave a benefit for the patient? Hepatogastroenterology. 1996;43:944–948.
- Luman W, Cull A, Palmer KR. Quality of life in patients tented for malignant biliary obstructions. Eur J Gastroenterol Hepatol. 1997;9:481–484.
- Abraham NS, Barkun JS, Barkun AN. Palliation of malignantbiliary obstruction: a prospective trial examining impact onquality of life. Gastrointest Endosc. 2002;56:835–841.
- Ware JE, Snow KK, Kosinski M, Gandek B. SF-36 health surveymanual and interpretation guide. Boston: The Health Institute, New England Medical Center; 1993. p. 87.
- Kass R, Raftery A. Bayes factors. J Am Stat Assoc 1995;90:773-95.
- Rege RV. Adverse effects of biliary obstruction: implications for treatment of patients with obstructive jaundice. AJR Am J Roentgenol. 1995;164:287–293.
- Kramer HJ. Impaired renal function in obstructive jaundice:roles of the thromboxane and endothelin systems. Nephron.1997;77:1–12.
- Jiang WG, Puntis MC. Immune dysfunction in patients withobstructive jaundice, mediators and implications for treatment.HPB Surg. 1997;10:129–142.
- Cotton PB, Schmitt C. Quality of life in palliative management of malignant obstructive jaundice. Scand J Gastroenterol.1993;199:44–46.
- Moss AC, Morris E, Leyden J, et al. Malignant distal biliaryobstruction: a systematic review and meta-analysis of endoscopicand surgical bypass results. Cancer Treat Rev. 2007;33:213–221.
- Yeoh KG, Zimmerman MJ, Cunningham JT, et al. Comparative costs of metal versus plastic biliary stent strategies for malignant obstructive jaundice by decision analysis. Gastrointest 1999;49: 466–471.
- Ballinger AB, McHugh M, Catnach SM, et al. Symptom reliefand quality of life after stenting for malignant bile ductobstruction. Gut. 1994;35:467–470.
- Luman W, Cull A, Palmer KR. Quality of life in patients tented for malignant biliary obstructions. Eur J Gastroenterol Hepatol. 1997;9:481–484
- Abraham NS, Barkun JS, Barkun AN. Palliation of malignant biliary obstruction: a prospective trial examining impact on quality of life. Gastrointest Endosc. 2002;56:835–841.
- Davids P, Groen A, Rauws F, Tytgat GN, Huibregtse K.Randomised trial of self-expanding metal stents versus polyethylene stents for distal malignant biliary obstruction. Lancet 1992;340:1488-92.
Corresponding Author
Rajesh R.U
Madras Medical College, Chennai, India