Title: ACUTE AND SUB ACUTE TOXICITY STUDY ON SIDDHA DRUG CUṆṬIYĀTI CŪRAṆAM
Authors: Dr Sheela E, Dr Manoharan A, Dr Komalavalli T, Santhanakumar M
DOI: https://dx.doi.org/10.18535/jmscr/v9i6.20
Abstract
The bronchial Asthma is the most common disease in India, because our country have more industrial area . It is the most common in allergic disease of human beings leading to more complication. The present study was investigated the acute sub-acute toxicity study of cuṇṭiyāti cūraṇam for the management of CUVĀCA KĀCAM (Bronchial Asthma), following OECD guidelines 423 and 407 method 28 days repeated oral toxicity studies were done on both sex of Wister albino rats.In acute and sub-acute toxicity studies no toxic effects were observed upto the dose level of 2000 mg/kg body weight and carried in five different groups in CC was administrated and dose ranging from 5, 50, 300, 1000, 2000 mg/kg for rat respectively. No mortality effect was observed up to 2000 mg/kg of body weight in acute and sub-acute toxicity study.
Keywords: cuṇṭiyāti cūraṇam, acute toxicity, sub-acute toxicity.