Atypical hemolytic uremic syndrome has a genetic predisposition. Pregnancy is a trigger to develop the disease and is a rare entity. It leads to hemolysis in microvasculature, acute renal failure, and thrombocytopenia. The disease is associated with a poor prognosis and needs early treatment initiation. 34-year-old P₄L₂ with post-partum hemorrhage was managed at our centre following which she had acute kidney injury, thrombocytopenia, and repeated fall in hemoglobin. A diagnosis of P-aHUS was made after ruling out other differentials and she was managed with hemodialysis and plasma exchange.

Keywords: pregnancy, atypical hemolytic uremic syndrome, eculizumab, plasma exchange.

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Dr Tanvi Katoch

Senior Resident, Department of Obstetrics and Gynecology, PGI, Chandigarh, India