HF with concomitant diabetes mellitus may have further increase risk through different pathophysiologic, hemodynamic and neurohormonal abnormalities

Aim: To evaluate the clinical presentation of patients with heart failure who were also diabetic.

Method: 100 patients coming with signs and symptoms of HF who were diabetic, between May 2018 to April 2019 were selected.

Results: Among them 64 were male and 36 were female. All patients had SOB, next common symptoms were swelling. Commonest sign found in our patients were edema, second most common finding were basal crepitations. In our study 39 patients with LVEF >50% had HbA1c between 6% -9%. However 46 patients with this level of HbA1c had LVEF <50%. P value was >0.5 which was not significant. In our study the association between HbA1c and NYHA class was not significant.  In our study we found that as HbA1c level goes up there were more chances of diastolic dysfunction. P value was < 0.5, which is statistically significant.

Conclusion: Although DM and HF are each individually associated with considerable morbidity and mortality, they often occur together, which further worsens adverse patient’s outcomes, quality of life, and cost of care.

Keywords: Heart failure, Diabetes mellitus, HaemoglobinA1C (HbA₁c), Diabetic Cardiomyopathy, diastolic dysfunction, left ventricular (LV) hypertrophy.

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Dr Bhim Ram

Assistant Professor, Deptt of General Medicine, IGIMS, Sheikhpura, Patna, Bihar, India