Title: Spectrum of Interstitial Lung Disease on High Resolution Computed Tomography- A Cross-Sectional Analysis
Authors: Dr Madhumita Chandrasekaran, Dr Anand.A.M., Dr Kulasekaran Nadhamuni, Dr Vasanthapriya Janarthanan, Dr Mohamed Rafi Kathar Hussain
DOI: https://dx.doi.org/10.18535/jmscr/v9i2.31
Abstract
Introduction
Interstitial lung disease (ILD) which is also known as diffuse infiltrative lung disease is a group of disorders which includes more than 200 entities mainly affecting the pulmonary interstitium in the lung parenchyma1. Pulmonary interstitium is the network of connective tissue fibers that supports the lung which includes interlobular septa, alveolar walls, and the peri-bronchovascular interstitium. It is characterized by interlobular/ interlobularseptal thickening, fibroblast proliferation, and pulmonaryfibrosis1.
Clinically they most commonly present with shortness of breath, dry cough, fatigue, and discomfort in the chest. The chest radiograph which is the initial imaging modality shows diffuse interstitial patterns like reticular, nodular, or reticulonodular opacities. In about 10 to 20 % of patients, a chest radiograph was found to be normal, even though lung biopsy was found to be positive2. Hence high resolution computed tomography of thorax is important in early diagnosis of interstitial lung disease with the assessment of its types and severity.
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