Abnormal uterine bleeding is one of the most common problems in perimenopausal age group. The proportion is 9-30% in reproductive age group. This proportion rises to 70% in perimenopausal and postmenopausal women. Abnormal uterine bleeding (AUB) warrants a thorough evaluation in perimenopausal women and hence it’s important to perform it in a cost-effective manner with available resources.

Aims and Objectives: Compare the efficacy of endometrial cytology with hysteroscopy guided biopsy.

Inclusion Criteria: women above 35 years of age with symptoms suggestive of AUB.

Exclusion Criteria: Pregnant patient and patient with genital tract infection, coagulation disorder and genital malignancy.

Conclusion: Endometrial sampling using Pipelle is an easy and safe method. It has high sensitivity, specificity, positive and negative predictive values when compared to hysteroscopy. Thus, to obtain adequate endometrial sample, Pipelle biopsy should be considered as primary investigation.

Keywords: Abnormal uterine bleeding, FIGO, PALM-COEIN.

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Prof Dr Debahuti Mohapatra