Objective: Comprehensive statistics on gynaecological malignancies reported from India are deficient. This study was performed to ascertain the clinicopathological profile of gynaecological cancers reported at our centre.

Materials and Methods: All women attending gynaecological OPD and radiotherapy OPD of TDMCH, Alappuzha who were diagnosed to have malignancy of the cervix, endometrium, ovary and other malignancy of the genital tract are taken as cases and those women without malignancy as excluded by pap smear, ultrasound examination and endometrial sampling are taken as controls. These population are studied for one year period from

Jan 2016 to Jan 2017.

Results: Of the population studied, ovarian malignancy were the commonest malignancy at our centre constituting about 39.8% of the population followed by endometrial and cervical cancer which constitutes about 35.2% and 23.6% respectively. Vulval cancer constitutes about 1.4% The histopathology of various

malignancy were studied and it was found that squamous cell carcinoma of cervix, endometrioid carcinoma of corpus uteri and epithelial ovarian malignancy remains to be the most common clinical type among each group constituting for about 68.75%, 54.16% and 75% respectively. Among the ovarian cancer serous cystadenocarcinoma ovary constitutes about 62.96% .Among the tumour markers studied CA125 is found to be significantly elevated in epithelial ovarian malignancy.

Conclusion: Thus to conclude ovarian and endometrial cancer is on the rise compared to cervical cancer.

Keywords: Gynaecological cancer; clinicopathologic profile; ovarian, endometrial and cervical cancer.

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Dr Priyadarsini. S

Assistant Professor, Dept. of Obstetrics & Gynaecology, Govt. Medical College, Trivandrum