Objective: The purpose of present study was to evaluate the RBS, ALP, and zinc in the individuals having T2DM and to compare the study parameters with healthy controls of Bundelkhand region. The other aim was to analyze the association between study parameters in healthy control subjects group and T2DM subjects group.

Results: We observed an insignificant in age in the present study when compared between the two groups. Whereas, comparison between two groups, of parameters such as the values of RBS, ALP, and serum zinc we observed a significant difference. In the patient group, positive correlation was observed between ALP versus zinc and a negative correlation was observed between age and RBS; RBS and serum zinc. In the control group, we found positive correlation between ALP and zinc.

Conclusion: In conclusion, we have demonstrated as zinc depletion aggravates insulin resistance and may result in increased loss through urine, it may be advisable to periodically monitor zinc concentrations in T2DM subjects.

Keywords: Type 2 Diabetes mellitus, Alkaline phosphatase, Hyperglycemia, Zinc.

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Dr Prabhakar Singh Bais

Asst Prof. & Head, Department of Biochemistry -MLB Medical College & Hospital- JHANSI-284128