Title: A Clinicopathological Study of Penile Carcinoma in a Tertiary Care Hospital, Visakhapatnam

Authors: Dr Bogarapu Chaitanya Babu,M.S, Dr Chintagada Jayaraj, M.S.,Mch, Dr Yeeli Sivaram Shashank, Dr Ginjupalli Sai Chand, Dr Potireddy Yaswanth Reddy, Dr Jami Yaswanth Sai, Dr Gopisetty Siri, Dr Munagala Poornima Aishwarya

 DOI: https://dx.doi.org/10.18535/jmscr/v9i1.18

Abstract

 

Background: One of the countries with the highest incidence of penile cancer in the world is India, with rates up to 3.32 per 100 000 men in some regions. The vast majority of patients have an apparently localized disease at diagnosis, with high-risk characteristics for nodal involvement but without clinical evidence of such involvement. This suggests that the morbidity and mortality among these patients is underestimated.

Materials and Methods: A retrospective study was conducted on 30 cases of carcinoma penis in the Department of General Surgery, King George Hospital, Visakhapatnam, from June 2018 to June 2020. Patients presenting with symptoms suggestive of carcinoma penis were admitted, investigated using routine investigations, and USG/CT scan, and managed during this period. Factors studied were incidence among age, demography, time of presentation, presenting complaints, stage of presentation, and treatment options available in our setup.

Results: Out of 30 subjects,14(46.66%) are aged above 60 yrs,10(33.33%) are between 30 - 44yrs,6(20%) are between 45 - 59yrs. 10(20%) subjects presented with phimosis. 20 subjects are smokers. Stage of presentation:: STAGE 0: 4 (13.33%), STAGE 1 : 6 (20%) ,STAGE 2 : 6 (20%), STAGE 3A : 2(6.66%),STAGE 3B : 8(26.66%),STAGE 4: 4 (13.33%). Lymph nodal involvement is noted in 12(40%) cases. Carcinoma insitu 4 (13.33%),Well differentiated squamous cell carcinoma 12 (40%), Moderately differentiated squamouscell carcinoma 12 (40%), spindle cell carcinoma 2 (6.66%). Penectomy alone (Total/Partial): 20(66.66%) cases. Penectomy with inguinal block dissection (Unilateral/Bilateral): 8(26.66%) cases. Chemoradiation: 2(6.66%) cases

Conclusion: Though the disease condition is rare in younger populations it’s not uncommon in developing nations. Early diagnosis and treatment significantly reduce the morbidity. Lack of awareness and social stigmas plays key role in delayed presentation. Active surveillance and awareness programs help in reducing the disease burden. Smoking, as in many diseases, is a significant risk factor for carcinoma penis, its usage should be condemned

Keywords: penile cancer, phimosis, squamous cell carcinoma, penectomy.

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